There is a transgender area on this board.

From my limited experience, I'd say the biggest impact between GD and Bipolar, is that HRT could switch you or make a depression or elation have greater magnitude. But if your pdoc's onboard, they can manage to compensate well enough.

I'll add a funny note as well, my hormone doc originally wanted to keep my T up near 70 ng/dL but once bipolar was also on the chart, completely lost interest and was happy with it being as low as it was. (10ng/dL suppressed)

Everyone's experience is different of course, but HRT is sufficient for me to be comfortable, so for now, I'm unlikely to push it further in the social space.