i have rx for both 25mg and 50 mg seroquel..usually 1/2 of a 25mg seroquel puts me to sleep easily but if i'm very stressed/anxious, i'll need the other 1/2 of 25mg seroquel which does the trick.

i cut the 50mg of seroquel in 1/4 so the dosage is about the same as cutting the 25mg of seroquel in 1/2...but i have noticed that the last 2 nights of using 1/4 of the 50 mg seroquel has done the opposite of sedating me: it has activated rather than sedated.

can the brand of 50mg cause the activation? cannot figure out why i'm not getting similar sleep when cutting the 50mg in 1/4. would appreciate any input or info.