If I'm understanding the question correctly, you are asking if a decreased appetite is worth crippling anxiety? Only you can answer that question I'm afraid. I would be inclined to say it's not worth it but I don't know your weight and corresponding health and mental issues enough to make such a determination. I'm staying off Wellbutrin currently because I can't handle the increased anxiety at this time. For me the anxiety issue diminishes though so I plan to try it when more stable. For you it doesn't seem the anxiety goes away and for me that would be an unacceptable side effect. (((Hugs)))