I'm "supposed" to take my Wellbutrin twice a day at 150mg and like you I often have to skip my second dose because it makes me so jumpy and a massive tremor. I'd shake so bad my family thought I was drinking again. Or if I'm at a store and have to hand over money it just shakes like crazy and it's embarrassing. I'd say just go at a pace that feels ok for you. I definitely get what you're going through. As far as appetite goes, I don't think I ate for like 2 days when I first started it but after a week or so my appetite went back to normal.