I have gained 70 lbs due to high prolactin and insulin resistance caused by invega. I struggled with restricting calories and could NOT lose weight, and in fact continued to gain. The only thing that works for me is low carb. I lost almost 20lbs from low carb but fell off the wagon and have gained most of it back. I'm going back on low carb soon as soon as I can find the motivation. Low calorie just doesn't work at all for me.