I am on Day 7 of Deplin 15mg daily. I, too, had the testing that shows that I have the MTHFR mutation that prevents my body from producing methylfolate.
Not sure if I'm seeing anything, and hopefully there's still a chance I will see something.
I've read stories where people see almost immediate results within a few days, and I've read it sometimes takes a couple of weeks.
I'm curious to read more personal experiences.

Thanks!
Rudy