I'm sorry you are estranged from your son. I hadn't read your back story. Do you know where the irritability and sadness is coming from? You need support. What about a therapist, family or friends? Is it specific or generalized? I'm glad you're not depressed. If this irritability and sadness continues in a strong manner for several days you might want to contact your pdoc. I hope you start feeling better soon. Irritation is painful. Thinking of you.