I would really encourage you to get in touch with your pdoc and therapist to get some relief. You have to be miserable. The only other things I know to do is to exercise to the point of exhaustion or to take some sleeping pills and try to sleep for more than an hour or two. I'm really sorry you're having such a tough time. I hope you feel better soon.
I can understand not getting out and not getting to appointments. That happens with me as well. Good luck and best wishes.