I'm sorry you're feeling so bad. I'm really sorry Latuda didn't help you as it has helped me and I was hoping to read the end of that sentence to say that you would be able to try it. I was on seroquel for awhile, too and it just made me feel over drugged and I wrecked two cars in one summer while taking it. I don't blame you for not wanting seroquel. I hope your pdoc can offer you some options. I know time seems to go by so slowly when you're feeling so low but keep fighting, keep posting here. I hope the depression lifts soon and that you find some enjoyment on your birthday.