When Wellbutrin stopped working for me, my doctor switched me to Trintellix. It works really good in it's place, however, I don't know anything about the sexual side effects. (meds effect everyone differently - I haven't had any, though) They both work on the same receptors or something. Trintellix is different than other AD's, my pdoc said because it's a modulator for 5 receptors or something like that.