So when I saw my pdoc this week, and I asked her if it would be okay to taper down on Seroquel. I am going to be taking 300 mg instead of 400 mg. In the winter, I was on 600 mg. The higher doses were making me feel too weird before bed: too lightheaded and powerful a feeling, although I absolutely need it for sleep. If I do not use Seroquel, I don't get any sleep, and that turns into mania real fast.

I do feel better on the lower dose of Seroquel, but just prior to my dose being lowered, I noticed I've been fighting more with family daily. Yes, my mother and I clash at times, but little things that normally I'd be able to brush off make me extremely angry, and I get louder, more agitated, reactive...and it's hard to de-escalate. I'm still on the highest dose of Lamictal, Gabapentin, and I take Klonopin as needed....but haven't even really taken it lately.

It's almost every day lately. Even today when my best friend said something that was irritating, I almost flew off the handle by getting defensive quick. I guess that's the word that describes me a lot: defensive. Anyway, I went from feeling decent to falling to pieces within a few hours today. Tears, anger, low self-esteem. I am definitely in need of support, and don't really know where to turn.

You've all been very helpful. I am wondering: do you think the fact my dose of Seroquel was lowered could be contributing to these mood swings? It was only lowered a couple of days ago. I don't know if I need to go back to my pdoc since I've just seen her Monday. It's hard keeping up with appointments with my work schedule and being able to match up with my pdoc's schedule. Has anyone experienced something like this before with a lower dose of an AP?