Seroquel is really sedating; at least I found it so. I currently take ziprasidone and trintellix and get really good results with that combination. But it does take time to figure out what works -- and sometimes what works changes on you.

I've been dealing with my bipolar diagnosis for 23 years and I want to tell you that it does get easier over time. The biggest thing that works is honesty with your psychiatrist so you can have the meds adjusted as often as is needful.

Good luck.