I've not had too much trouble with weight gain with clozapine at a moderate dose. I gained about 10 lbs. inititally and have 5 more that I go up and down with. I'm on metformin and that halted the gaining. My doctor doesn't want me on more metformin because my blood sugar might get too low on it. So while I complain about it because I really hate those 10-15 lbs and the one pants size increase they mean, compared to other meds it's not bad. I'm hoping that as my dose goes down some in the next few months that my weight will too.

I also just accept that I'm going to be on a med that causes weight gain; the ones that don't failed me long ago. I hate it but it is what it is and feeling good is worth some annoyance.