I'm trans, but AFAB (assigned female at birth). Anyway, I hope I'm not intruding on this board, but I can definitely offer insight to this topic.

The short answer is: YES! It definitely can be.

The long answer is: Anecdotal, but after I had my baby I was put on Depo by my request. I thought it would be a good option, but it wasn't. It's similar to the mini pill (progesterone only). Anyway, on Depo I was miserable. I had a period three weeks out of a month (I'd have one one week, have a break, have another, then have a short break, and so on). It was light bleeding for me, but it never stopped. It was usually spotting. Some days, it was period like bleeding other days just seemed to be breakthrough. It was hard to tell when I was having a period and when I wasn't because I was PMSing and cramping ALL THE TIME.

It, also, worsened my anxiety to the point where I literally felt like I was losing my mind. Pair this with postpartum hormones and I was a mess.

When the 3 months were done, I decided I never wanted to touch depo again. The mood swings, bleeding, and weight gain were too much. So, I went on the mini pill. Other than the implant (which I refuse) the mini pill was the only other one safe while breastfeeding.

But it wasn't any better. I spotted nonstop. My periods, at least, seemed to subside for the most part. But when they did come, I got severely depressed. I would lay in bed and do nothing but cry. I didn't want to take care of my baby, I didn't want to be touched by my partner, all I wanted to do was sleep. This went on for four months on the mini pill. Then, I stopped taking it. And I've been better off without birth control.

I'm sensitive to side effects (with birth control, psychiatric meds, even Tylenol). So, I don't think BC is for me at all. I have just been using condoms, and since I'm in a monogamous relationship sometimes we just track my cycle to know when I'm ovulating and pull out or abstain. I know pull out isn't 100% effective, but it's worked so far (admittedly the fact that we don't have sex often probably plays a part in that).

Tip: Do not go on Depo. If y ou're reacting this badly to the mini pill, Depo will probably be 10x worse.