The ketamine trial I participated in did nothing for me. First, I had to go through the screening process. That took at least a month. Then there was the placebo treatment, which obviously had no effect.

Finally it was time for the real thing. I did it twice a week for a month and saw no benefit to my mood or my depression related chronic pain. Each time I did it, I'd trip out less and less, since your body gets used to it quickly and builds a tolerance. But I wasn't there to trip out.

The only positive, besides getting paid, was that I felt less inhibited for approximately an hour after its administration (nasal). This was nice since my social anxiety is a contributor to my depression. Still, only a few hours after I left the treatment facility, I felt the same.

This shouldn't dissuade you from trying though. Just don't spend any money on it. I personally know someone who this worked for. I'm just a hard case I guess.

By the way, throughout the process you cannot admit to having any serious suicidal thoughts or else they kick you out of the study. My guess is that's true in most trials. So keep that in mind.

Anyway, the pay was pretty good, so at least there's that. I still worked part time when I was doing it. It just didn't work for me.

P.s. You can't drive for 24 hours after the dose so they gave me rides free of charge. Can't speak for other trials.