I am prescribed 150 mg trazadone. I break them in half and take one shortly before bed. If I don't fall asleep quickly, I take the other half. If I am still awake ~45 minutes after that, I can take another half if I have an already broken one (this is the brilliantly simple way to make sure I am not averaging over 150 mg per night). 225 mg is the max she wants me to take and at that dose (and to some degree even at 150) there is a definite trade-off in that I will be groggy for a couple of hours in the morning. Sometimes even that won't do it on the first coupe of nights of an episode, but by the 3rd night it will (because of the exhaustion).