I've had BPD and Major Depression for 10 years now, and have gone though many different combos of meds. The combo that seems to help for me is:

Seroquel 100mg 3x a day, 200mg @ bedtime
Depakote 500mg 3x a day
Paxil 20mg 1x a day

It's different for everyone, but this combo reduces my thoughts of self injury.