I have found it has been helpful to an extent. It seemed to enable me to feel some positive feelings for a change, something I hadn't felt in a long time, but it is not consistent in this effect. I take it on an as needed basis which is not what was recommended, but it does seem to have an ability to change thought patterns. sometimes 1/4 mg is enough to notice, but it does seem to give me minor facial twitches at higher doses, so I am cautious with it. I got really wiped out with 1mg, but maybe I should just follow doctor's advice and take the1mg a day