I just started low dose Saphris last week. So far, it is working pretty well. A good night's sleep and wake alert; even if waken during the night, which is very bizarre. Pricey, though. Even with a coupon it was $292 for 30. But I am only taking a half a pill a night. Still roughly $5 a pop. I am going to fight the insurance company before the refill. I probably wouldn't have picked it up at that price, but my wife did. She has had some bad experiences with me not taking prescribed meds. Really bad. Like pay that without blinking bad.