The sympathetic nervous system is what gets the body ready to react, and is primarily activated by a release of norepinephrine. This handles the physiological changes. After that the parasympathetic nervous system is activated to handle the aftereffects.
Seriously, there's a great write-up on Wikipedia that handles everything from the physical to the cognitive effects. No research needed, it's all been done for you.
Amazing what a 5-second google search can give you.
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Meds: Latuda, Lamictal XR, Vyvanse, Seroquel, Klonopin
Supplements: Monster Energy replacement.  Also DLPA, tyrosine, glutamine, and tryptophan
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