Thanks for all your responses. I started Lithium yesterday. I'm starting to feel better. Maybe the Lamictal kicked in or the idea that I finally decided to try Lithium has given me hope for stability.

Rose76 I agree that with depression their could be something going on other than inside the brain's neurochemistry. For me there is a ton going on and there ale=ways has been. My Pdoc always asks if there is any significant change or major event going on in my life that is causing me distress and I say no. If something did change I know I would feel better.