I used to get horrific, torture-like full body akathisia on Seroquel.
I am now using it again, 8 years later, but with Atarax (a strong antihistamine). At first I would wake up from jerky knee shakes, but it went away. I take 25 mg of Atarax at bedtime, together with Seroquel. Atarax is a very benign med and I would try it first.
Beta blockers (atenolol, propranolol) gave me dangerously low blood pressure, so they are out for me. I have not tried Cogentin for akathisia.
Tardive akathisia sounds super scary...
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Dx: Bipolar I w/Psychotic Features
Rx: Seroquel ER 550 mg, Depakote ER 1000 mg, Melatonin 6 mg, Atarax 50 mg.
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