All you can do is be honest with your friends....tell them you are worried about them because you care.....offer advise and suggest they seek treatment. I've been helped many times when I didn't want help.....I've been hospitalized against my will or received unsolicited advise from well meaning people that had a huge effect. It's not always true that you have to want help to be helped.....and even if your friend doesn't listen to you now they might remember what you said in the future and be helped simply by recalling That you cared enough to do something rather than nothing. As another poster mentioned, they might get mad at you but as long as your heart is in the right place, you should know you did the right thing. I'm sorry to hear your friends are unwell and hope they get the care they deserve, whether they know what's good for them or not.