That's interesting. I have noticed my frustration limit seems to have gotten lower over the last couple of years. I thought it was just having a lot thrown at me all at once and also not being willing to tolerate certain abusive behaviors from family. But I also started taking seroquel a few years ago. I take a pretty high dose, for mood/psychosis and also tardive dyskensia. Iv e also noticed more crying, not from depression usually but more frustration, which has always been what would make me cry in the past.