hi. tranquilizers in general are known for calming agitation, reducing anxiety, and inducing a degree of apathy and emotional indifference. The more sedating tranquilizers, such as seroquel, also cause a lot of sedation, so that often (but not always...) helps with agitation, anxiety, intense mood states, etc.

If one reads the literature, though, it seems that there are problems with tranquilizers. Some people get such intense akathisia that they engage in violent behavior, even homicide, assaults, and suicides. Short of full on akathisia, many people report intense drug induced dysphoria from these drugs, and that can cause problems, too. Some data from back in the day showed that people diagnosed with "Bipolar I" treated with long acting injections of the older drugs cycled into depression more frequently than those not so treated.

Personally, Seroquel was a nightmare for me. I had nightmares while sleeping, and I'd wake up sweaty, with stiff muscles. I was over-sedated and angry during the day. Looking back, I think I'm quite prone to akathisia and dysphoria, so the heavy sedation probably just made things worse, not better.

10% reduction of dose is a good way to go, especially with more potent drugs, such as seroquel and other tranquilizers. On the plus side, seroquel is low potency, so its easier to cut the dosage more slowly, more exactly, and then adjust to life with less and less tranquilizer on board. On the downside, seroquel is densely sedating and affects all kinds of neurotransmitters, so tapering can be rough on some people.

I'm glad you have some talking treatments going on in your life. That's a very good thing, especially since you're aiming to cut the seroquel ((always a good thing, if one can...)).