i think metformin is a good idea, also. zyprexa is a bit more effective than most other 'atypical' tranquilizers, in large studies, but the metabolic effects are definitely a big, big problem.

i did see some small abstracts from very small studies that seemed to suggest that some high dose, high potency antioxidants--I think one study used a lot of alpha lipoic acid, another used high dose green tea extract--could help prevent some metabolic problems, when taken alongside ongoing zyprexa treatment.

it also seems that a lot of doctors end up switching people who develop metabolic problems to other drugs, such as abilify or geodon, now and then a low to moderate dose of an older tranquilizer, such as perphenazine.