I took Saphris for something like six years. Always took the black cherry flavor, and I don't care how they try to cover up the taste it is nasty. Worked for me for all that time, but I got off it because I developed tardive dyskenesia, which went away after a few months off the Saphris. I now take Vraylar and it has worked well for the 8 months or so I've been on it. The only real side effect I am getting with the Vraylar is I have developed anxiety since I've been on it...may be coincidence.