hi. definitely see if you can get some blood work done. the obvious stuff--blood sugar, trigylcerides, total cholesterol, etc.--and whatever else the doctor might recommend.

some people can lose weight by taking metformin, a diabetes drug, with their ongoing tranquilizer treatment. not all shrinks are keen on prescribing metformin, but it does seem to work for a lot of people.

other than that...i don't have any major suggestions. low to moderate doses of some of the older tranquilizers work well for a lot of people, w/o the metabolic effects of seroquel and many other 'atypicals.' loxapine is one example of such a drug, as is perphenazine. the problem there is the risk for eps (twitches, tremor, etc.) and tardive dyskinesia (which is often permanent), but...the risk for the older drugs might have been exaggerrated in some studies by using excessively high doses of Haldol, which is notorious for causing those problems.

I hope you+your doctor(s) can find a good solution.