I was on Saphris for years, then switched to Vraylar after developing TD on Saphris.

I have taken Vraylar for awhile, at the usual starting dose of 3 mg. It is super expensive, like Saphris, so you'll need good insurance. It is a small capsule, not that nasty dissolving tablet like Saphris. Vraylar has a very long half life, so if you are bad about taking meds, it takes a LONG time to get out of your system (half life is 2-4 DAYS!!). It has helped me with my symptoms very well. As far as side effects go, the only ones I really have are a little lightheadedness (which is not particularly bothersome, I just know it's there) and I have anxiety now which I did not have on Saphris. I wonder if Saphris medicated the anxiety or Vraylar is causing it...unsure about that and so is my pdoc. Anxiety is a listed side effect for Vraylar.

Of course everyone is different. All you can do is try these meds to see which one works for you.

FYI, in addition to Vraylar I take lithium and Lamictal.