Thread: Risperdal
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Old Sep 08, 2017, 11:40 AM
still_crazy still_crazy is offline
Grand Poohbah
 
Member Since: Oct 2016
Location: United States of America
Posts: 1,792
hi. im sorry about that. Abilify...and I would think the other D2 partial agonists, too...are great for some people, but then...well, for a lot of people, they've been a real let down.

there are other tranquilizers, both old ("conventional") and new(er) ("atypical"). 2mgs/risperidone isn't a whole lot, but...I also found the stuff mind-numbing. A bigger concern for me was prolactin elevation...and all the metabolic stuff.

some of the older tranquilizers help, as long as the dose is kept low(ish). perphenazine is often well-tolerated, as is loxapine. I had an acquaintance who did surprisingly well on Navane, but..honestly, I don't know if that stuff is even still on the market.

zyprexa is somewhat more effective in Schizophrenia than risperidone, in big studies. that comes at a big price, in terms of metabolic problems. some doctors prescribe metformin, a drug used for diabetes type II, w/ zyprexa (and sometimes other tranquilizers, too) to reduce weight gain and reduce the other risks associated with treatment. i just thought id mention that because zyprexa doesn't cause eps or td as often as risperidone, and a lot of people report benefits in mood, anxiety, overall mental state.

amoxapine is a tca antidepressant that does double duty as a tranquilizer. its chemically related to loxapine. i saw a small study, done in mexico back when all the 'atypicals' were too expensive for many nations, that compared amoxapine (high dose) to standard dose risperidone, in schizophrenia. the amoxapine was just as well-tolerated, with more pronounced benefits in mood, anxiety, and I think sleep, too.

if you have good insurance, there's 2 new D2 partial agonists out there that may or may not be helpful for you. wish i could provide more helpful info., but...these drugs are very new. some people who didn't do so well on abilify seem to do well on the newer D2 partial agonists, for some reason.

hope this helps.