I've been on all of them but I can't recall what my experience was because it was too long ago, back in the '80's.and early '90's. I had lots of trouble with meds in those days but to be fair they were always adding high doses of ADs and benzos into the mix so it could have been the combination of meds that was the problem. About 10 yrs ago I wised up and refused any more ADs in any form and I've had less problems but they used the atypical APs. I do hear that the old drugs get good results and they use lower doses than they used to.