Within 2.5 weeks on 300 I was already documenting some warning signs like colors looking very vivid, sleep deteriorating(even with a sleeping pill), lots of dancing and admiring how hot I am lol. Gradually increased but took a dive to depression at week 6 for 1 week. This may have been due to pms and throwing up almost all of my food for a month though(not on purpose I was just very sick and didnt want wellbutrin taken away so I didnt go to the dr for 3 weeks). That is when I quit taking my sleeping pill because I was sleeping fine and then I just didnt go back on it when I probably should have. Week 7 started climbing again and I am at week 10 now.