I have been on Wellbutrin SR for about 5 years. Lots has happened over the past 5 years (death of father, awful job, better job change, etc), and Wellbutrin has seemed to work fine - for the most part. Most of my issues seem to lie in anxiety/derealization - just feeling disconnected when I think about how we are here and then we aren't/existential stuff that can't really be helped. However, I do fall in these ruts (not sure of a better word) where I can't seem to ever sleep enough, and I just cry all the time. Over. Everything. This is one of those times when I had a really big feeling the last time would really, truly be the last. This feels a lot more difficult than the other times. I can barely watch TV shows, listen to music, etc. I can barely make it through the work day without thinking about all the hardships my students and the others in their class will inevitably face and ducking into the bathroom to cry. It's like these sad, true thoughts get stuck in my brain.

I am not suicidal and have no plans or anything like that. But I do have this passing thought some times that it would be great to just stop feeling so much. I would never do anything. It's honestly just a thought. I have been diagnosed with depression before - and was put on Wellbutrin during one of these ruts I am describing.

I have made a lot of changes over the past few months also - for example, I haven't drank any alcohol in almost 130 days. And I am proud of myself because this is a time I would be drinking a lot, and right now, I would like to just drink a bottle of wine, but I'm not. So I am more confused why I am feeling this way.

Could Wellbutrin be losing its effectiveness? Has it lost effectiveness for anyone here? I take the SR 150 mg twice daily.

Do you think therapy would help? I have been in and out of therapy - I had experiences with one therapy whose focus was positive psychology that was honestly life changing. However, it has been difficult to find that. Also - can I hear some thoughts and experiences regarding online therapy? Or should I do that on another thread?

Thanks to everyone. I am scheduling an appointment with my new primary doctor to discuss this. Just wanted to ask other people too.