I've heard Geodon is supposed to be taken twice a day 12 hours apart. This was ideally what the psychiatrist wanted. However, my endocrinologist has me taking thyroid medication in the morning and says it's best to not to take any other medication for four hours afterward or else it could lessen the effectiveness. So I've been taking one dose of Geodon at noon and one dose at dinner which is only about 6 hours apart. I thought of taking the second dose of Geodon later, such as before bed, but I've also heard Geodon works better when taken with food. Is it so terrible to take Geodon 6 hours apart? I'll have to talk to both doctors about this but was just wondering what others thought.