I am also on 100mg of Seroquel. It does absolutely nothing for me. Some days it will knock me out within 2 hours, other days it doesn't knock me out at all. I have been on it for 2 months and I have actually lost weight but it does vary person to person for the weight gain.

I have heard some get Seroquel munchies shortly after taking the dosage if they don't go to sleep right away but I haven't experienced this. To me, this pill is more like a sugar pill (minus the nights it does work to help me sleep).