Did they try titration? It looks like I am going to end up at 200mg. 300mg made me slightly hypo, then I found out I should have split the dose (using 75mg tabs to titrate) and when I did that I still felt off and really drained by the end of the day. But 225mg is treating me pretty good. It's pulling me out of the funk and it is helping with appetite suppression. I have lost 14# (still need to lose a lot more).