I was a little surprised that 300 was problematic as I had taken that much before but that was when I was pretending it was unipolar depression and didn't have lamictal bringing up my mood also. I may go higher at some point. It took over 6 weeks for me to settle with the lamictal. Like NatsukiKuga, I kind of enjoyed the euphoric hypomania. I was really bummed when I finally took a deep dive but only stayed deeply depressed for 6 days. Weird. But trying 300mg of wellbutrin recently, I got one day of euphoric hypomania and 2 days of feeling like crap. I have been backed off to 225 for a few days and mood is good. When I get the 200s, I will have a bunch of 75s left so I could add one a day if I started feeling depressed. I will talk to the psych NP about that, but I don't think she will have a problem with it since she was letting me self titrate,