So just really a check in for folks that followed a few of my earlier threads. I was taking lamotrigine, Cymbalta and seroquel for sleep. We pulled out the Cymbalta, replaced with Abilify and have a prn of xanax. It has been a good change and even is finally where I am. My last depressed episode ran months so this is a nice change of pace finally. I've made med changes in the past (been fighting this since 2005) and it seems whenever a change is made, I do well for a while. I hope this is more permanent this go around.