Hi, I'm Bipolar and I've found that Seroquel does help but I'm also on Trileptal which is actually an epilepsy medication but I'm not epileptic. I was put on it as a mood stabilizer and I find it helps the most with my mood and paired with the Seroquel has been the winning combo for me. I also default to depression but these meds have been keeping me in check for once! I take:
Seroquel 25 mg 3 x daily
Trileptal 600 mg 2 x daily
Seroquel 200 mg at night
Hope this helps!