I can understand where you are coming from. I feel very conflicted when it comes to Seroquel. Literally, I feel scared some nights, where I feel almost paralyzed in a semi-conscious state before it knocks me out. It's hard to describe. It mainly happened when I was on high doses though, compared to now. I was getting twitchy, dopey, and gained weight on doses that were higher, but luckily, a dosage change did help. Some days, I'm completely fine, but I don't really like how it feels at night. It's the only thing that helps with sleep consistently and mixed mania though, but I hate being so dependent on something for sleep.

EDIT: I just decided to take a 100mg tablet that I have that's old, but not too old to be effective. Although it's quite low compared to the dosage I am on, it's a compromise to avoid the heavier sedation, just for tonight. Hopefully it won't screw me up by skipping the higher dose, but maybe it won't since at least I took a portion of it, instead of not taking any at all.