Avoid MAOI’s if you are an especially anxious person or prone to insomnia. I had a horrific experience with them and they had bad psychological effects on me (anger, manic-like moods at night, irritability) as well as severe insomnia for 9 months. (I was on EMSAM for 18 months altogether).

My pdoc - who did not prescribe the MAOI - helped me come off of it and he said that MAOI’s boost your levels of norepinephrine like crazy, almost like amphetamines