There are two ways to deal with this, and the fact of the matter is, there are ALWAYS going to be jerks in the workplace, and sometimes, they will be your supervisor. I would suggest using a medium-chill setting with her. Meaning, you listen to her directives, and let everything else she says go, just set her on ignore. Medium-chill is like treating her like a young child who just says things that you aren't going to engage with. So no matter what she throws at you, you just don't engage her, you just let it go.

The other thing you can do is talk to a manager or someone higher up. You have to be careful when you do this though so that YOU don't get labeled the troublemaker, since she has seniority.

Good luck,
Seesaw