Latuda didn't work for depression for me. I was taking it with geodon at the time and got the tardive stuff but that's cause of too many APs. I went off the geodon and it went away. In the end though I was on 160 mg and still depressed and psychotic so we tried fanapt for a week to get rid of the psychosis but it didn't work and i gained 10 lbs. I ended going back on geodon. geodon seems to be the only thing that helps with the psychosis. when i get manic i take saphris, but currently I'm off that but have a whole stash if something happens.