I don't know a lot on the subject, but I have a cousin who suffers from it. His mother always said it was sweets that set it off in him. It too affected his toes, and then his whole foot if he did not heed the warning signs.
Could try a google search or the Mayo Clinic site for more information, they have tons of links there to lead you to a good source of information.
Good luck, hope he conquers!
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