hi. me again. lamictal usually becomes more calming/tranquilizing at higher doses. low doses are used to boost antidepressants, higher doses are more common in people with bipolar i, lots of agitation, etc.

wellbutrin is a more stimulating drug for depression. it has its pros and cons, one 'pro' being it seems to cause fewer 'switches' into (hypo)mania than, say, prozac or the tca drugs. but that's looking at large groups of people. individual results vary, of course.

TD can be a major problem. people w/ bipolar I are more prone to both acute eps and td, over the long haul. maybe a sedating, low(er) potency tranquilizer? seroquel/seroquel xr comes to mind. zyprexa has a low td rate. there's symbyax, which is just zyprexa and prozac (together at last...), in a number of different dosages.

since you're on klonopin already, maybe ask about a switch to a more sedating benzodiazepine? 2mgs/klonopin=(roughly...) 40mgs/valium. Valium acts faster than Klonopin, has a long half-life, is more sedating, and I think also has more pronounced muscle relaxant (spelling?) properties. ativan is also commonly used in psychosis, agitation, (hypo)mania, etc. one problem w/ klonopin over the long haul is the potential for drug-induced depression.

im stuck on an 'atypical' tranquilizer, myself. im prone to eps and scared of td. i take tons of high dose antioxidants, b-vitamins, etc. w/ the tranquilzier. i now tolerate the abilify w/o eps, my anxiety is much better, and i do not have td, akathisia, stiff gait, any of that stuff. if you're interested in that sort of thing, here's a link to a website w/ free information : DoctorYourself.com: Andrew Saul's Natural Health Website

hope this helps.