I'm in week 10 or so of trialling seroquel in an attempt to treat the depressive phase. My baseline mood and ability to bounce back from setbacks are a lot better with seroquel, but I'm ultrarapid cycling. No bones about it.
I've also developed days of feeling keyed up in a weird physical sense, where I tend to develop severe irritability or sometimes euphoria.
These issues are not bad enough to stop gathering data. We need to understand the effect of the seroquel better. I went up 50% after the first 4 weeks. At the higher dose, according to my mood tracking, the good effects didn't get better side effects got worse. So now I'm back to the initial dose to see what happens.
I suspect next month if I'm still super unstable, maybe we'll pull me off the lamictal and try another stabilizer to try to level the instability but keep the antidepressant effect of the seroquel.
I dug up some recent medication treatment recommendations for the Canadian health system and that's the next step they recommend, adding something like lamictal or depakote to seroquel.
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Bipolar II ultrarapid cycling + ADHD-PI, both treatment resistant af
zyprexa 2.5 / dexedrine 10 / valium 3 :: CYP2D6 poor metabolizer
currently trialing meds one by one with a great pdoc after 20 years of fail
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