Quote:
Originally Posted by ~Christina
Thanks !
I tried MTX starter dose and everything was fine , took full dose the following week and it sent my liver functions through the roof, my doctors were very worried and had me do daily blood work for a week.
I am scared of the biologics. Guess that will be a pretty long discussion with my Doctor. We might decide that just living with the PsA Pain along with fibro would be safer. Mix it all with my psych BP meds ? Who knows what the hell would/could happen.
Ugh !
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I am sorry about your experience with MTX.

Labs are critical.
I keep thinking about that, too. I'll bet "they" have no idea how the biologics mix with psych meds, and esp the newer biologics and the newer psych meds. It's a crap shoot!
I am afraid of biologics, too. Very much so.
That said, I'd try them under the guidance of my rheumy if MTX fails. Why? I am severely affected by PsA. I cannot walk w/o methotrexate or a med fighting the PsA process. I have put off both MTX and biologics for so long now, I am in the position of either using a med which helps or being in a wheelchair (not just in the future, but now). The pain is excruciating even at rest. So far, MTX helps and all labs are good. I went from a wheelchair to walking 2 miles at a time. The reason I am on a second trial is: I'd stopped it for 10 wks to see if it was adding to severe depression.
Much more is known about the older biologics. My rheumy states she has pts doing fine on Humira for 10 years. I dunno.
Uggh! Uggh! Uggh! Is right!
I am sorry you are having to suffer and having to make these types of choices.

WC