I take a Lithium/Seroquel combo. Lithium twice a day. Seroquel four times a day. It's the only combo that has worked for me.
Lithium doesn't make me sleepy at all. I know many people don't like Lithium. I am very thankful for it.
However with Seroquel I feel hungover in the morning. I need to sleep 8-9hrs to feel awake. I also don't function without caffeine in the morning.