This is an old thread but I just wanted to chime in and say I experienced derealization and depersonalization on Lamictal. I started googling it again because it's been a really long time since I was on it and I was actually thinking of trying it again since it is weight neutral. I'm Bipolar II and I'm not currently on a mood stabilizer. I take Abilify but that's not really a true mood stabilizer and antipsychotics are bad for weight gain.

So... I just talked myself out of trying it again. I also had a scary episode of hearing voices which is also a rare side effect.

No thanks.