Yes... I can relate to this. My head of chucked full of negative, self-loathing thoughts. The difference (perhaps?) is that, in my case, they're all perfectly justified. I'm an older person now & I no longer have any significant goals either.

For a long time, I tried to work on my self-loathing thoughts. But, over time, I've just come to a point where I realize their never going to go away. So I do what I can in the moment work with them in a compassionate, accepting manner. But I'm not putting any organized effort into it. I'm a reclusive old troll. So I rarely go out. I consider my solitude to be my gift to the world... or at least that tiny portion of it I inhabit.